ZDHHC7 AntibodyСпецификацияОбъем | 100 мкл | Синонимы | EC 2.3.1.-, ZDH7, ZDHC7, zinc finger 370, ZNF370 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | Q9NXF8 | Иммуноген | Synthesized peptide derived from C-terminal of human ZDHHC7. | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB,WB:1:500-1:3000 | Примечание | Palmitoyltransferase with broad specificity. Palmitoylates SNAP25 and DLG4/PSD95. May palmitoylate GABA receptors on their gamma subunit (GABRG1, GABRG2 and GABRG3) and thereby regulate their synaptic clustering and/or cell surface stability By similarity. Palmitoylates sex steroid hormone receptors, including ESR1, PGR and AR, thereby regulating their targeting to the plasma membrane. This affects rapid intracellular signaling by sex hormones via ERK and AKT kinases and the generation of cAMP, but does not affect that mediated by their nuclear receptors.<br/><br/>Ota T., Nat. Genet. 36:40-45(2004).<br/>The MGC Project Team, Genome Res. 14:2121-2127(2004).<br/>Sjoeblom T., Science 314:268-274(2006)<br/> | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Области исследований | Neuroscience,Signal transduction | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from HUVEC cells, using ZDHHC7 antibody.
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