| Объем | 100 мкл |
| Синонимы | Neuronal tryptophan hydroxylase, NTPH, Tryptophan 5- monooxygenase 2, |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q8IWU9 |
| Иммуноген | Synthesized non-phosphopeptide derived from human TPH2 around the phosphorylation site of serine 19 (G-FI-S(p)-L-D). |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB,WB:1:500-1:3000 |
| Примечание | This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. The human genome contains two related tryptophan hydroxylases, one on chromosome 11p15-p14 and one on chromosome 12q21. This gene is expressed predominantly in the brain stem. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression.<br/><br/>Bader M., Science 299:76-76(2003).<br/>Gibbs R.A., Nature 440:346-351(2006).<br/>Pandey A., Proc. Natl. Acad. Sci. U.S.A. 104:2199-2204(2007).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Neuroscience |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HuvEc cells (Lane 2), using TPH2 (Ab-19) antiobdy. The lane on the left is treated with systhesized peptide.
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Наименование: TPH2 (Ab-19) Antibody.