Объем | 50 мкг |
Синонимы | Thiopurine S-methyltransferase (EC 2.1.1.67) (Thiopurine methyltransferase), TPMT |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P51580 |
Иммуноген | Recombinant Human Thiopurine S-methyltransferase protein (4-244AA) |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA |
Примечание | TPMT is an enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals. A pseudogene for this locus is located on chromosome 18q. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Biotin |
Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | >95%, Protein G purified |
Абревеатура | Thiopurine S-methyltransferase protein |
Области исследований | Metabolism, Signal transduction |
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