Объем | 100 мкл |
Синонимы | TNF receptor-associated factor 4, Cysteine-rich domain associated with RING and Traf domains protein 1, Malignant 62, RING finger protein 83, TRAF4 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q9BUZ4 |
Иммуноген | Synthesized peptide derived from internal of human TRAF4. |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB,WB:1:500-1:3000 |
Примечание | Adapter protein and signal transducer that links members of the tumor necrosis factor receptor (TNFR) family to different signaling pathways. Plays a role in the activation of NF-kappa-B and JNK, and in the regulation of cell survival and apoptosis. Regulates activation of NF-kappa-B in response to signaling through Toll-like receptors. Required for normal skeleton development, and for normal development of the respiratory tract By similarity. Required for activation of RPS6KB1 in response to TNF signaling. Modulates TRAF6 functions.<br/><br/>Tomasetto C.L., Genomics 28:367-376(1995).<br/>Miller H.G., Submitted (AUG-1998) to the EMBL/GenBank/DDBJ databases.<br/>Cai C.L., Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases.<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Cancer,Cell biology,Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from 3T3 cells, using TRAF4 antibody.
|
| |