TFEB Antibody, Biotin conjugatedСпецификация| Объем | 100 мкг | | Синонимы | Transcription factor EB (Class E basic helix-loop-helix protein 35) (bHLHe35), TFEB, BHLHE35 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P19484 | | Иммуноген | Recombinant Human Transcription factor EB protein (1-476AA) | | Источник | Rabbit | | Видовая специфичность | Human | | Применение | ELISA | | Примечание | Transcription factor that specifically recognizes and binds E-box sequences (5'-CANNTG-3'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. In association with TFE3, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes and binds the CLEAR-box sequence (5'-GTCACGTGAC-3') present in the regulatory region of many lysosomal genes, leading to activate their expression. It thereby plays a central role in expression of lysosomal genes. Acts as a positive regulator of autophagy by promoting expression of genes involved in autophagy. Specifically recognizes the gamma-E3 box, a subset of E-boxes, present in the heavy-chain immunoglobulin enhancer. Plays a role in the signal transduction processes required for normal vascularization of the placenta. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Biotin | | Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | >95%, Protein G purified | | Абревеатура | Transcription factor EB | | Области исследований | Epigenetics and Nuclear Signaling, Tags & Cell Markers | | Ссылка на страницу на сайте производителя | ссылка | | | |
Информация для заказа| Область использования: | Производство: | Cusabio | | Метод: | Антитела | | Объем: | 100 мкг | | Кат. номер: | CSB-PA023429ED01HU | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: TFEB Antibody, Biotin conjugated.
Примечание: дополнительная информация (на английском языке). |
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