TGFB2 AntibodyСпецификацияОбъем | 50 мкл | Синонимы | transforming growth factor, beta 2 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P61812 | Иммуноген | Synthetic peptide of human TGFB2 | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, IHC,ELISA:1:2000-1:5000, IHC:1:25-1:100 | Примечание | This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types by transducing their signal through combinations of transmembrane type I and type II receptors (TGFBR1 and TGFBR2) and their downstream effectors, the SMAD proteins. Disruption of the TGFB/SMAD pathway has been implicated in a variety of human cancers. The encoded protein is secreted and has suppressive effects of interleukin-2 dependent T-cell growth. Translocation t(1,7)(q41,p21) between this gene and HDAC9 is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. The knockout mice lacking this gene show perinatal mortality and a wide range of developmental, including cardiac, defects. Alternatively spliced transcript variants encoding different isoforms have been identified. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antigen affinity purification | Области исследований | Others | Ссылка на страницу на сайте производителя | ссылка | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA274133(TGFB2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ?200)
| The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA274133(TGFB2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ?200)
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