| Объем | 100 мкл |
| Синонимы | E12, ITF1, Immunoglobulin enhancer binding factor E12/E47, Immunoglobulin transcription factor-1, Kappa-E2-binding factor |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P15923 |
| Иммуноген | Synthesized peptide derived from C-terminal of human TCF3. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 |
| Примечание | Transcriptional regulator. Involved in the initiation of neuronal differentiation. Heterodimers between TCF3 and tissue-specific basic helix-loop-helix (bHLH) proteins play major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Dimers bind DNA on E-box motifs: 5'-CANNTG-3'. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer. Binds to IEB1 and IEB2, which are short DNA sequences in the insulin gene transcription control region.<br/><br/>Kamps M.P., Cell 60:547-555(1990).<br/>Nourse J., Cell 60:535-545(1990).<br/>Grimwood J., Nature 428:529-535(2004). |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Epigenetics and Nuclear Signaling,Stem cells |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from 293 cells, using TCF3 antibody.
 |
Immunohistochemistry analysis of paraffin-embedded human brain tissue using TCF3 antibody.
 |
| | |
Наименование: TCF3 Antibody.