| Объем | 100 мкл |
| Синонимы | RTEF1, TCF13L1, TEA domain family member 4, TEAD-4, TEAD4 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q00059 |
| Иммуноген | Synthesized peptide derived from internal of human TFAM. |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, IHC, IF,IHC:1:50-1:100, IF:1:100-1:500 |
| Примечание | Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind DNA. Bends the mitochondrial light strand promoter DNA into a U-turn shape via its HMG boxes. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA.<br/><br/>Parisi M.A., Science 252:965-969(1991).<br/>Tominaga K., Biochim. Biophys. Acta 1131:217-219(1992).<br/>Fisher R.P., J. Biol. Chem. 267:3358-3367(1992).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Epigenetics and Nuclear Signaling,Cancer,Cardiovascular,Tags & Cell Markers,Metabolism,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue, using TFAM antibody.
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Immunofluorescence analysis of HepG2 cells, using TFAM antibody.
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Наименование: TFAM Antibody.