| Объем | 100 мкл |
| Синонимы | dual specificity protein kinase TTK, EC 2.7.12.1, Esk1, Mps1, MPS1L1 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P33981 |
| Иммуноген | Synthesized non-phosphopeptide derived from human TTK around the phosphorylation site of threonine 676 (D-T-T(p)-S-V). |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 |
| Примечание | Phosphorylates proteins on serine, threonine, and tyrosine. Probably associated with cell proliferation. Essential for chromosome alignment by enhancing AURKB activity (via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint.<br/><br/>Mills G.B., J. Biol. Chem. 267:16000-16006(1992).<br/>Ota T., Nat. Genet. 36:40-45(2004).<br/>Mungall A.J., Nature 425:805-811(2003)<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Epigenetics and Nuclear Signaling,Cell biology |
| Ссылка на страницу на сайте производителя | ссылка |
Immunohistochemistry analysis of paraffin-embedded human brain tissue using TTK (Ab-676) antibody.
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Western blot analysis of extracts from HUVEC cells, treated with etoposide (25uM, 24hours), using TTK (Ab-676) antibody.
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Western blot analysis of extracts from colo cells (Lane 2), using TTK (Ab-676) antiobdy. The lane on the left is treated with synthesized peptide.
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Наименование: TTK (Ab-676) Antibody.