Объем | 50 мкг |
Синонимы | TERF1-interacting nuclear factor 2 (TRF1-interacting nuclear protein 2), TINF2, TIN2 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q9BSI4 |
Иммуноген | Recombinant Human TERF1-interacting nuclear factor 2 protein (210-451AA) |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA |
Примечание | Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends, without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Plays a role in shelterin complex assembly. Isoform 1 may have additional role in tethering telomeres to the nuclear matrix. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | FITC |
Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | >95%, Protein G purified |
Абревеатура | TERF1-interacting nuclear factor 2 |
Области исследований | Epigenetics and Nuclear Signaling |
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