UBA2 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | ANTHRACYCLINE-associated resistance ARX, ARX, EC 6.3.2.-, SUMO-1 activating enzyme subunit 2, UBA2 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q9UBT2 | | Иммуноген | Synthesized peptide derived from C-terminal of human Uba2. | | Источник | Rabbit | | Видовая специфичность | Human | | Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 | | Примечание | The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.<br/><br/>Mark H. L. Lambermon, Mol. Cell. Biol., Jun 2002, 22: 4346 - 4357. <br/>Kyoung-Seok Ryu, J. Biol. Chem., Sep 2003, 278: 36621 - 36627. <br/>R. Jrgen Dohmen, J. Biol. Chem., Jul 1995, 270: 18099. <br/>Yoshiaki Azuma, FASEB J, Jun 2001, 10.1096.<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Cell biology | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from 293 cells, treated with UV (5mins), using Uba2 antibody.
 | Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using Uba2 antibody.
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Наименование: UBA2 Antibody.