Объем | 100 мкл |
Синонимы | Tumor necrosis factor receptor superfamily, member 1B |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P20333 |
Иммуноген | Fusion protein of human TNFRSF1B |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB,ELISA:1:1000-1:2000, WB:1:200-1:1000 |
Примечание | The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen affinity purification |
Области исследований | Cancer,Cell biology,Immunology,Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
Gel: 10%SDS-PAGE, Lysate: 40 ?g, Lane: Human colon cancer tissue, Primary antibody: CSB-PA234429(TNFRSF1B Antibody) at dilution 1/150, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
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