| Объем | 100 мкл |
| Синонимы | EFP, Efp, Estrogen responsive finger protein, TRI25, TRIM25 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q14258 |
| Иммуноген | Synthesized peptide derived from internal of human ZNF147. |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB,WB:1:500-1:3000 |
| Примечание | Functions as a ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates 'Lys-63'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection. Promotes ISGylation of 14-3-3 sigma (SFN), an adapter protein implicated in the regulation of a large spectrum signaling pathway. Mediates estrogen action in various target organs.<br/><br/>Inoue S., Proc. Natl. Acad. Sci. U.S.A. 90:11117-11121(1993).<br/>The MGC Project Team, Genome Res. 14:2121-2127(2004).<br/>Rush J., Nat. Biotechnol. 23:94-101(2005).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Epigenetics and Nuclear Signaling,Cell biology,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from K562 cells, using ZNF147 antibody.
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Наименование: TRIM25 Antibody.