| Объем | 100 мкл |
| Синонимы | alpha isozyme, DNA topoisomerase II, DNA topoisomerase II-alpha, P11388-1, TOP-2 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P11388 |
| Иммуноген | Synthesized non-phosphopeptide derived from human TOP2A around the phosphorylation site of threonine 1343 (E-K-T(p)-D-D). |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB,WB:1:500-1:3000 |
| Примечание | Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes.<br/><br/>Tsai-Pflugfelder M., Proc. Natl. Acad. Sci. U.S.A. 85:7177-7181(1988).<br/>Wasserman R.A., Cancer Res. 53:3591-3596(1993).<br/>Lang A.J., Gene 221:255-266(1998).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Epigenetics and Nuclear Signaling,Cancer |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HepG2 cells, using TOP2A (Ab-1343) antibody.
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Western blot analysis of extracts from K562 cells (Lane 2), using TOP2A (Ab-1343) antiobdy. The lane on the left is treated with synthesized peptide.
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Наименование: TOP2A (Ab-1343) Antibody.