Объем | 100 мкл |
Синонимы | USP6 N-terminal-like protein, Related to the N-terminus of tre, RN-tre, USP6NL, KIAA0019 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q92738 |
Иммуноген | Synthesized peptide derived from internal of human USP6NL. |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, IHC,IHC:1:50-1:100 |
Примечание | Acts as a GTPase-activating protein for RAB5A and RAB43. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for structural integrity of the Golgi complex.<br/><br/>Wong W.T., Oncogene 12:2563-2571(1996).<br/>Nomura N., DNA Res. 1:27-35(1994).<br/>Lanzetti L., Nature 408:374-377(2000)<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using USP6NL antibody.
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