Объем | 50 мкг |
Синонимы | Bone morphogenetic protein 10 (BMP-10), BMP10 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | O95393 |
Иммуноген | Recombinant Human Bone morphogenetic protein 10 protein (317-424AA) |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA |
Примечание | Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | HRP |
Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | >95%, Protein G purified |
Абревеатура | Bone morphogenetic protein 10 |
Области исследований | Cardiovascular, Signal transduction |
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