Объем | 50 мкл |
Синонимы | WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein), WDR5, BIG3 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P61964 |
Иммуноген | Recombinant Human WD repeat-containing protein 5 protein (1-334AA) |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB, IHC, Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200 |
Примечание | Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen Affinity Purified |
Области исследований | Epigenetics and Nuclear Signaling |
Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: WDR5 antibody at 2µg/ml + A431 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 37 kDa
Observed band size: 37 kDa
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Immunohistochemistry of paraffin-embedded human breast tissue using CSB-PA026038ESR2HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human thyroid tissue using CSB-PA026038ESR2HU at dilution of 1:100
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