WEE1 Antibody, HRP conjugatedСпецификация| Объем | 50 мкг | | Синонимы | Wee1-like protein kinase (WEE1hu) (EC 2.7.10.2) (Wee1A kinase), WEE1 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P30291 | | Иммуноген | Recombinant Human Wee1-like protein kinase protein (45-177AA) | | Источник | Rabbit | | Видовая специфичность | Human | | Применение | ELISA | | Примечание | Acts as a negative regulator of entry into mitosis (G2 to M transition) by protecting the nucleus from cytoplasmically activated cyclin B1-complexed CDK1 before the onset of mitosis by mediating phosphorylation of CDK1 on 'Tyr-15'. Specifically phosphorylates and inactivates cyclin B1-complexed CDK1 reaching a maximum during G2 phase and a minimum as cells enter M phase. Phosphorylation of cyclin B1-CDK1 occurs exclusively on 'Tyr-15' and phosphorylation of monomeric CDK1 does not occur. Its activity increases during S and G2 phases and decreases at M phase when it is hyperphosphorylated. A correlated decrease in protein level occurs at M/G1 phase, probably due to its degradation. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | HRP | | Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | >95%, Protein G purified | | Абревеатура | Wee1-like protein kinase | | Области исследований | Epigenetics and Nuclear Signaling, Cell biology | | Ссылка на страницу на сайте производителя | ссылка | | | |
Информация для заказа| Область использования: | Производство: | Cusabio | | Метод: | Антитела | | Объем: | 50 мкг | | Кат. номер: | CSB-PA16059B0Rb | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: WEE1 Antibody, HRP conjugated.
Примечание: дополнительная информация (на английском языке). |
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