BRAF AntibodyСпецификация| Объем | 50 мкл | | Синонимы | V-raf murine sarcoma viral oncogene homolog B1 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P15056 | | Иммуноген | Synthetic peptide of human BRAF | | Источник | Rabbit | | Видовая специфичность | Human, Mouse | | Применение | ELISA, WB, IHC,ELISA:1:1000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200 | | Примечание | This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antigen affinity purification | | Области исследований | Cancer,Cell biology,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA179620(BRAF Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: ?200)
 | The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using CSB-PA179620(BRAF Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: ?200)
 | Gel: 8%SDS-PAGE, Lysate: 50 ?g, Lane 1-2: Hela cells, HT29 cells, Primary antibody: CSB-PA179620(BRAF Antibody) at dilution 1/1400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes
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Наименование: BRAF Antibody.