Объем | 100 мкл |
Синонимы | Zinc finger CCCH domain-containing protein 8, ZC3H8, ZC3HDC8, |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q8N5P1 |
Иммуноген | Synthesized peptide derived from internal of human ZC3H8. |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 |
Примечание | Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene By similarity. Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.<br/><br/>Zhuang D.Z., Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases.<br/>The MGC Project Team, Genome Res. 14:2121-2127(2004).<br/>Hwang E.S., Immunology 106:464-469(2002).<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Epigenetics and Nuclear Signaling |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HepG2 cells, using ZC3H8 antibody.
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Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using ZC3H8 antibody.
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