Объем | 50 мкл |
Синонимы | Vacuolar protein sorting-associated protein 33B (hVPS33B), VPS33B |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q9H267 |
Иммуноген | Recombinant Human Vacuolar protein sorting-associated protein 33B protein (348-617AA) |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB, IHC, Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200 |
Примечание | May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes. Mediates phagolysosomal fusion in macrophages (PubMed:18474358). Proposed to be involved in endosomal maturation implicating VIPAS39. In epithelial cells, the VPS33B:VIPAS39 complex may play a role in the apical recycling pathway and in the maintenance of the apical-basolateral polarity (PubMed:20190753). Seems to be involved in the sorting of specific cargos from the trans-Golgi network to alpha-granule-destined multivesicular bodies (MVBs) promoting MVBs maturation in megakaryocytes (By similarity). |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen Affinity Purified |
Абревеатура | Vacuolar protein sorting-associated protein 33B |
Области исследований | Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: VPS33B antibody at 2.72µg/ml
Lane 1: Hela whole cell lysate
Lane 2: A549 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 71, 61 kDa
Observed band size: 71, 61 kDa
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Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA884447ESR2HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA884447ESR2HU at dilution of 1:100
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