Объем | 100 мкг |
Синонимы | Vam6/Vps39-like protein (TRAP1-like protein) (hVam6p), VPS39, KIAA0770 TLP VAM6 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q96JC1 |
Иммуноген | Recombinant Human Vam6/Vps39-like protein (263-490AA) |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, WB, IHC, IF, Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
Примечание | Regulator of TGF-beta/activin signaling, inhibiting SMAD3- and activating SMAD2-dependent transcription. Acts by interfering with SMAD3/SMAD4 complex formation, this would lead to inhibition of SMAD3-dependent transcription and relieve SMAD3 inhibition of SMAD2-dependent promoters, thus increasing SMAD2-dependent transcription. Does not affect TGF-beta-induced SMAD2 or SMAD3 phosphorylation, nor SMAD2/SMAD4 complex formation. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | >95%, Protein G purified |
Абревеатура | Vam6/Vps39-like protein |
Области исследований | Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
Western Blot
Positive WB detected in: Mouse heart tissue, Mouse kidney tissue
All lanes: VPS39 antibody at 3µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 102, 101 kDa
Observed band size: 102 kDa
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Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA836235LA01HU at dilution of 1:100
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Immunofluorescent analysis of A549 cells using CSB-PA836235LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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