TYK2 (Ab-1054) AntibodyСпецификация| Объем | 100 мкл | | Синонимы | tyrosine kinase 2, JTK1, | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P29597 | | Иммуноген | Peptide sequence around aa.1052~1056 (H-E-Y-Y-R) derived from Human TYK2. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, IHC,IHC:1:50-1:100 | | Примечание | <p>TYK2 encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. <br /><br />Zheng H, et al. (2005) Mol Cell Proteomics. 4(6):721-730. <br />Gauzzi MC, et al. (1996) J Biol Chem. 271(34): 20494-20500.</p> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. | | Области исследований | Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using TYK2(Ab-1054) Antibody(left) or the same antibody preincubated with blocking peptide(right).
 | | | |
Информация для заказа |
Наименование: TYK2 (Ab-1054) Antibody.