| Объем | 100 мкл |
| Синонимы | Ubiquitin-conjugating enzyme E2 T, Ubiquitin-protein ligase T, Ubiquitin carrier protein T, UBE2T, |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q9NPD8 |
| Иммуноген | Synthesized peptide derived from internal of human UBE2T. |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB,WB:1:500-1:3000 |
| Примечание | Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes monoubiquitination. Involved in mitomycin-C (MMC)-induced DNA repair: acts as a specific E2 ubiquitin-conjugating enzyme for the Fanconi anemia complex by associating with E3 ubiquitin-protein ligase FANCL and catalyzing monoubiquitination of FANCD2, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCL and FANCI. May contribute to ubiquitination and degradation of BRCA1. In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, but may prefer 'Lys-11'-, 'Lys-27'-, 'Lys-48'- and 'Lys-63'-linked polyubiquitination.<br/><br/>Okaze H., Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases.<br/>Hu R.-M., Proc. Natl. Acad. Sci. U.S.A. 97:9543-9548(2000).<br/>Zhang Q.-H., Genome Res. 10:1546-1560(2000).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Epigenetics and Nuclear Signaling,Cell biology |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HeLa cells, Jurkat cells and K562 cells, using UBE2T antibody.
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Наименование: UBE2T Antibody.