Объем | 100 мкл |
Синонимы | Ubiquitin recognition factor in ER-associated degradation protein 1 (Ubiquitin fusion degradation protein 1) (UB fusion protein 1), UFD1, UFD1L |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q92890 |
Иммуноген | Recombinant Human Ubiquitin recognition factor in ER-associated degradation protein 1 protein (1-307AA) |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB, IHC, Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200 |
Примечание | Essential component of the ubiquitin-dependent proteolytic pathway which degrades ubiquitin fusion proteins. The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. It may be involved in the development of some ectoderm-derived structures. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen Affinity Purified |
Абревеатура | Ubiquitin fusion degradation protein 1 homolog |
Области исследований | Cell biology |
Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: UFD1 antibody at 3.22µg/ml
Lane 1: HepG2 whole cell lysate
Lane 2: Raji whole cell lysate
Lane 3: MCF-7 whole cell lysate
Lane 4: Jurkat whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 35, 39, 30 kDa
Observed band size: 35 kDa
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Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA842166ESR1HU at dilution of 1:100
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