UHRF2 AntibodyСпецификацияОбъем | 50 мкг | Синонимы | E3 ubiquitin-protein ligase UHRF2, Np95/ICBP90-like RING finger protein, Np95-like RING finger protein, Nuclear protein 97, Nuclear zinc finger protein Np97, RING finger protein 107, RING-type E3 ubiquitin transferase UHRF2, Ubiquitin-like PHD and RING finger domain-containing protein 2, Ubiquitin-like-containing PHD and RING finger domains protein 2, UHRF2, NIRF, RNF107 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | Q96PU4 | Иммуноген | Recombinant Human E3 ubiquitin-protein ligase UHRF2 protein (444-585AA) | Источник | Rabbit | Видовая специфичность | Human | Применение | ELISA, IF, Recommended dilution: IF:1:50-1:200 | Примечание | E3 ubiquitin-protein ligase that is an intermolecular hub protein in the cell cycle network. Through cooperative DNA and histone binding, may contribute to a tighter epigenetic control of gene expression in differentiated cells. Ubiquitinates cyclins, CCND1 and CCNE1, in an apparently phosphorylation-independent manner and induces G1 arrest. Also ubiquitinates PCNP leading to its degradation by the proteasome. E3 SUMO-, but not ubiquitin-, protein ligase for ZNF131. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | >95%, Protein G purified | Абревеатура | E3 ubiquitin-protein ligase UHRF2 | Области исследований | Cell biology | Ссылка на страницу на сайте производителя | ссылка | Immunofluorescence staining of U251 cells with CSB-PA839395LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
| | |
Информация для заказа |