YWHAZ (Ab-58) AntibodyСпецификация| Объем | 100 мкл | | Синонимы | 1433Z, 143Z, FAS, Factor activating exoenzyme S, KCIP-1 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P63104 | | Иммуноген | Peptide sequence around aa.56~60 (R-S-S-W-R) derived from Human 14-3-3 zeta. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC,WB:1:500-1:1000, IHC:1:50-1:200 | | Примечание | This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene.<br/><br/>Gu YM, et al. (2006) FEBS Lett , 580(1): 305-310<br/>Powell DW, et al. (2003) Mol Cell Biol, 23(15): 5376-5387<br/>Mackintosh C. (2004) Biochem J, 381(Pt 2): 329-342.<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. | | Области исследований | Neuroscience,Cell biology,Tags & Cell Markers,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from HepG2 , Hela and 293 cells using 14-3-3z(Ab-58) Antibody.
 | Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using 14-3-3z(Ab-58) Antibody(left) or the same antibody preincubated with blocking peptide(right).
 | | | |
Информация для заказа |
Наименование: YWHAZ (Ab-58) Antibody.