ZNF207 Antibody, Biotin conjugatedСпецификацияОбъем | 100 мкг | Синонимы | BUB3-interacting and GLEBS motif-containing protein ZNF207 (BuGZ) (hBuGZ) (Zinc finger protein 207), ZNF207, BUGZ | Клональность | Polyclonal Antibody | Организм | Human | uniprot | O43670 | Иммуноген | Recombinant Human BUB3-interacting and GLEBS motif-containing protein ZNF207 protein (206-463AA) | Источник | Rabbit | Видовая специфичность | Human | Применение | ELISA | Примечание | Kinetochore- and microtubule-binding protein that plays a key role in spindle assembly (PubMed:24462186, PubMed:24462187, PubMed:26388440). ZNF207/BuGZ is mainly composed of disordered low-complexity regions and undergoes phase transition or coacervation to form temperature-dependent liquid droplets. Coacervation promotes microtubule bundling and concentrates tubulin, promoting microtubule polymerization and assembly of spindle and spindle matrix by concentrating its building blocks (PubMed:26388440). Also acts as a regulator of mitotic chromosome alignment by mediating the stability and kinetochore loading of BUB3 (PubMed:24462186, PubMed:24462187). Mechanisms by which BUB3 is protected are unclear: according to a first report, ZNF207/BuGZ may act by blocking ubiquitination and proteasomal degradation of BUB3 (PubMed:24462186). According to another report, the stabilization is independent of the proteasome (PubMed:24462187). | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Biotin | Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | >95%, Protein G purified | Абревеатура | BUB3-interacting and GLEBS motif-containing protein ZNF207 | Области исследований | Others | Ссылка на страницу на сайте производителя | ссылка | | |
Информация для заказаОбласть использования: | Производство: | Cusabio | Метод: | Антитела | Объем: | 100 мкг | Кат. номер: | CSB-PA026578LD01HU | Цена (с НДС 20%): | по запросу | В корзину | Наименование: ZNF207 Antibody, Biotin conjugated. Примечание: дополнительная информация (на английском языке). |
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