ACLY AntibodyСпецификацияОбъем | 50 мкл | Синонимы | ATP citrate lyase | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P53396 | Иммуноген | Fusion protein of human ACLY | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB,ELISA:1:2000-1:5000, WB:1:500-1:2000 | Примечание | ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antigen affinity purification | Области исследований | Cancer,Metabolism,Signal transduction | Ссылка на страницу на сайте производителя | ссылка | Gel: 6%SDS-PAGE, Lysate: 40 ?g, Lane 1-2: A172 cells, PC3 cells, Primary antibody: CSB-PA189814(ACLY Antibody) at dilution 1/1050, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds
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