ACTN1 AntibodyСпецификацияОбъем | 50 мкл | Синонимы | actinin, alpha 1 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P12814 | Иммуноген | Fusion protein of human ACTN1 | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, IHC,ELISA:1:1000-1:2000, IHC:1:15-1:50 | Примечание | Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antigen affinity purification | Области исследований | Developmental biology,Signal transduction,Stem cells | Ссылка на страницу на сайте производителя | ссылка | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA906019(ACTN1 Antibody) at dilution 1/10, on the right is treated with fusion protein. (Original magnification: ?200)
| The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA906019(ACTN1 Antibody) at dilution 1/10, on the right is treated with fusion protein. (Original magnification: ?200)
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