AKR1A1 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | AK1A1, AKR1A1, alcohol dehydrogenase, Alcohol dehydrogenase [NADP+], Aldehyde reductase | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P14550 | | Иммуноген | Synthesized peptide derived from C-terminal of human AKR1A1. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB,WB:1:500-1:3000 | | Примечание | Catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. Catalyzes the reduction of mevaldate to mevalonic acid and of glyceraldehyde to glycerol. Has broad substrate specificity. In vitro substrates include succinic semialdehyde, 4-nitrobenzaldehyde, 1,2-naphthoquinone, methylglyoxal, and D-glucuronic acid. Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs, including the anthracyclines doxorubicin (DOX) and daunorubicin (DAUN).<br/><br/>Bohren K.M., J. Biol. Chem. 264:9547-9551(1989).<br/>Fujii J., Cytogenet. Cell Genet. 84:230-232(1999).<br/>Barski O.A., Genomics 60:188-198(1999).<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Cancer,Cell biology,Metabolism,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from COLO205 cells and NIH-3T3 cells, using AKR1A1 antibody.
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Наименование: AKR1A1 Antibody.