AR (Ab-363) AntibodyСпецификацияОбъем | 100 мкл | Синонимы | ANDR, Androgen receptor, DHTR, Dihydrotestosterone receptor, NR3C4 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P10275 | Иммуноген | Synthesized non-phosphopeptide derived from human Androgen Receptor around the phosphorylation site of tyrosine 363 (D-Y-Y(p)-N-F). | Источник | Rabbit | Видовая специфичность | Human, Mouse | Применение | ELISA, WB,WB:1:500-1:3000 | Примечание | Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.<br/><br/>Lubahn D.B., Mol. Endocrinol. 2:1265-1275(1988).<br/>Lubahn D.B., Proc. Natl. Acad. Sci. U.S.A. 86:9534-9538(1989).<br/>Govindan M.V., Mol. Endocrinol. 4:417-427(1990).<br/> | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Области исследований | Epigenetics and Nuclear Signaling,Cancer,Developmental biology,Signal transduction | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from K562 cells, treated with EGF (200ng/ml, 5mins), using Androgen Receptor (Ab-363) antibody.
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