Объем | 50 мкл |
Синонимы | Acid-sensing ion channel 3 (ASIC3) (hASIC3) (Amiloride-sensitive cation channel 3) (Neuronal amiloride-sensitive cation channel 3) (Testis sodium channel 1) (hTNaC1), ASIC3, ACCN3 SLNAC1 TNAC1 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q9UHC3 |
Иммуноген | Recombinant Human Acid-sensing ion channel 3 protein (62-320AA) |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB, IHC, Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200 |
Примечание | Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Generates a biphasic current with a fast inactivating and a slow sustained phase. In sensory neurons is proposed to mediate the pain induced by acidosis that occurs in ischemic, damaged or inflamed tissue. May be involved in hyperalgesia. May play a role in mechanoreception. Heteromeric channel assembly seems to modulate channel properties. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen Affinity Purified |
Абревеатура | Acid-sensing ion channel 3 |
Области исследований | Neuroscience |
Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: ASIC3 antibody at 2.4µg/ml
Lane 1: Jurkat whole cell lysate
Lane 2: HepG2 whole cell lysate
Lane 3: Hela whole cell lysate
Lane 4: A549 whole cell lysate
Lane 5: A431 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 59, 61, 45 kDa
Observed band size: 59 kDa
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Immunohistochemistry of paraffin-embedded human melanoma using CSB-PA890688ESR1HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA890688ESR1HU at dilution of 1:100
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