BAX AntibodyСпецификация| Объем | 100 мкл | | Синонимы | Apoptosis regulator BAX, BAX, | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q07814 | | Иммуноген | Synthesized peptide derived from internal of human BAX. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC, IF,WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500 | | Примечание | The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.<br/><br/>Oltvai Z.N., Cell 74:609-619(1993).<br/>Apte S.S., Genomics 26:592-594(1995).<br/>Shi B., Biochem. Biophys. Res. Commun. 254:779-785(1999). | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Cancer,Cell biology,Metabolism | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from 293 cells, using BAX antibody.
 | Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue using BAX antibody.
 | Immunofluorescence analysis of HUVEC cells, using BAX antibody.
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Наименование: BAX Antibody.