BAZ2A Antibody, Biotin conjugatedСпецификацияОбъем | 50 мкг | Синонимы | Bromodomain adjacent to zinc finger domain protein 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3), BAZ2A, KIAA0314 TIP5 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | Q9UIF9 | Иммуноген | Recombinant Human Bromodomain adjacent to zinc finger domain protein 2A protein (97-266AA) | Источник | Rabbit | Видовая специфичность | Human | Применение | ELISA | Примечание | Essential component of the NoRC (nucleolar remodeling complex) complex, a complex that mediates silencing of a fraction of rDNA by recruiting histone-modifying enzymes and DNA methyltransferases, leading to heterochromatin formation and transcriptional silencing. In the complex, it plays a central role by being recruited to rDNA and by targeting chromatin modifying enzymes such as HDAC1, leading to repress RNA polymerase I transcription. Recruited to rDNA via its interaction with TTF1 and its ability to recognize and bind histone H4 acetylated on 'Lys-16' (H4K16ac), leading to deacetylation of H4K5ac, H4K8ac, H4K12ac but not H4K16ac. Specifically binds pRNAs, 150-250 nucleotide RNAs that are complementary in sequence to the rDNA promoter, pRNA-binding is required for heterochromatin formation and rDNA silencing (By similarity). | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Biotin | Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | >95%, Protein G purified | Абревеатура | Bromodomain adjacent to zinc finger domain protein 2A | Области исследований | Others | Ссылка на страницу на сайте производителя | ссылка | | |
Информация для заказаОбласть использования: | Производство: | Cusabio | Метод: | Антитела | Объем: | 50 мкг | Кат. номер: | CSB-PA883428HD01HU | Цена (с НДС 20%): | по запросу | В корзину | Наименование: BAZ2A Antibody, Biotin conjugated. Примечание: дополнительная информация (на английском языке). |
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