BCAR1 (Ab-410) AntibodyСпецификация| Объем | 100 мкл | | Синонимы | BCAR1, Breast cancer anti-estrogen resistance 1, CRK-ASSOCIATED SUBSTRATE, CRKAS, | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P56945 | | Иммуноген | Synthesized non-phosphopeptide derived from human p130 Cas around the phosphorylation site of tyrosine 410 (G-V-T-A-V). | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 | | Примечание | Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion. Implicated in induction of cell migration. Overexpression confers antiestrogen resistance on breast cancer cells.<br/><br/>Katarzyna Modzelewska, J. Biol. Chem., Dec 2006, 281: 37527 - 37535.<br/>Kevin Ogden, Am J Physiol Heart Circ Physiol, Dec 2006, 291: H2857 - H2863.<br/>Sangkil Nam, Cancer Res., Oct 2005, 65: 9185 - 9189.<br/>Norikazu Yamana, Mol. Cell. Biol., Sep 2006, 26: 6844 - 6 | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Cancer,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using p130 Cas (Ab-410) antibody.
 | Western blot analysis of extracts from NIH/3T3 cells, using p130 Cas (Ab-410) antibody.
 | Western blot analysis of extracts from HuvEc cells using p130 Cas (Ab-410) antibody. The lane on the left is treated with synthesized peptide.
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Наименование: BCAR1 (Ab-410) Antibody.