BICD2 Antibody, Biotin conjugatedСпецификацияОбъем | 100 мкг | Синонимы | Protein bicaudal D homolog 2 (Bic-D 2), BICD2, KIAA0699 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | Q8TD16 | Иммуноген | Recombinant Human Protein bicaudal D homolog 2 protein (511-625AA) | Источник | Rabbit | Видовая специфичность | Human | Применение | ELISA | Примечание | Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates and stabilizes the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track) (By similarity). Facilitates the binding of RAB6A to the Golgi by stabilizing its GTP-bound form. Regulates coat complex coatomer protein I (COPI)-independent Golgi-endoplasmic reticulum transport via its interaction with RAB6A and recruitment of the dynein-dynactin motor complex (PubMed:25962623). Contributes to nuclear and centrosomal positioning prior to mitotic entry through regulation of both dynein and kinesin-1. During G2 phase of the cell cycle, associates with RANBP2 at the nuclear pores and recruits dynein and dynactin to the nuclear envelope to ensure proper positioning of the nucleus relative to centrosomes prior to the onset of mitosis (By similarity). | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Biotin | Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | >95%, Protein G purified | Абревеатура | Protein bicaudal D homolog 2 | Области исследований | Signal transduction | Ссылка на страницу на сайте производителя | ссылка | | |
Информация для заказаОбласть использования: | Производство: | Cusabio | Метод: | Антитела | Объем: | 100 мкг | Кат. номер: | CSB-PA844723LD01HU | Цена (с НДС 20%): | по запросу | В корзину | Наименование: BICD2 Antibody, Biotin conjugated. Примечание: дополнительная информация (на английском языке). |
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