| Объем | 100 мкл |
| Синонимы | Biogenesis of lysosome-related organelles complex 1 subunit 6 (BLOC-1 subunit 6) (Pallid protein homolog) (Pallidin) (Syntaxin 13-interacting protein), BLOC1S6, PA PLDN |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q9UL45 |
| Иммуноген | Recombinant Human Biogenesis of lysosome-related organelles complex 1 subunit 6 protein (1-170AA) |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB, IHC, IP, Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IP:1:200-1:2000 |
| Примечание | Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particularly in the vesicle-docking and fusion process. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen Affinity Purified |
| Абревеатура | Biogenesis of lysosome-related organelles complex 1 subunit 6 |
| Области исследований | Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: BLOC1S6 antibody at 3.33µg/ml
Lane 1: A431 whole cell lysate
Lane 2: 293T whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 20, 9 kDa
Observed band size: 20 kDa
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Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA890745DSR2HU at dilution of 1:100
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Immunoprecipitating BLOC1S6 in HEK293 whole cell lysate
Lane 1: Rabbit monoclonal IgG (1µg) instead of CSB-PA890745DSR2HU in HEK293 whole cell lysate.
For western blotting, a HRP-conjugated anti-rabbit IgG, specific to the non-reduced form of IgG was used as the Secondary antibody (1/50000)
Lane 2: CSB-PA890745DSR2HU (4µg) + HEK293 whole cell lysate (500µg)
Lane 3: HEK293 whole cell lysate (20µg)
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Наименование: BLOC1S6 Antibody.