BMI1 AntibodyСпецификация| Объем | 50 мкл | | Синонимы | BMI1 polycomb ring finger oncogene | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P35226 | | Иммуноген | Fusion protein of human BMI1 | | Источник | Rabbit | | Видовая специфичность | Human, Mouse | | Применение | ELISA, WB,ELISA:1:1000-1:2000, WB:1:200-1:1000 | | Примечание | BMI1 polycomb ring finger oncogene, also known as BMI1, is a protein which in humans is encoded by the BMI1gene. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antigen affinity purification | | Области исследований | Epigenetics and Nuclear Signaling,Cancer,Cell biology,Stem cells | | Ссылка на страницу на сайте производителя | ссылка | Gel: 10%SDS-PAGE, Lysate: 40 ?g, Lane 1-4: 231 cells, A549 cells, hela cells, mouse brain tissue, Primary antibody: CSB-PA288653(BMI1 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
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Наименование: BMI1 Antibody.