Объем | 100 мкл |
Синонимы | B-RAF, B-RAF proto-oncogene serine/threonine-protein kinase, B-Raf proto-oncogene serine/threonine-protein kinase, BRAF, BRAF1 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P15056 |
Иммуноген | Synthesized non-phosphopeptide derived from human B-Raf around the phosphorylation site of threonine 735 (P-K-T(p)-P-I). |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, WB,WB:1:500-1:3000 |
Примечание | Protein kinase involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May play a role in the postsynaptic responses of hippocampal neuron. Phosphorylates MAP2K1, and thereby contributes to the MAP kinase signal transduction pathway.<br/><br/>Stephens R.M., Mol. Cell. Biol. 12:3733-3742(1992).<br/>Hillier L.W., Nature 424:157-164(2003).<br/>Eychene A., Oncogene 7:1657-1660(1992).<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Cancer,Cell biology,Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from rat brain cells, using B-Raf (Ab-753) antibody.
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