CCR5 AntibodyСпецификацияОбъем | 100 мкл | Синонимы | chemokine (C-C motif) receptor 5 (gene/pseudogene) | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P51681 | Иммуноген | Synthetic peptide of human CCR5 | Источник | Rabbit | Видовая специфичность | Human, Mouse | Применение | ELISA, IHC,ELISA:1:1000-1:2000, IHC:1:15-1:50 | Примечание | This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antigen affinity purification | Области исследований | Neuroscience,Cancer,Cardiovascular,Immunology,Microbiology,Signal transduction | Ссылка на страницу на сайте производителя | ссылка | The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA548882(CCR5 Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: ?200)
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