Объем | 50 мкл |
Синонимы | CD207 molecule, langerin |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q9UJ71 |
Иммуноген | Fusion protein of human CD207 |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB,ELISA:1:1000-1:2000, WB:1:200-1:1000 |
Примечание | The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen affinity purification |
Области исследований | Metabolism,Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
Gel: 8%SDS-PAGE, Lysate: 40 ?g, Lane: Human brain malignant glioma tissue, Primary antibody: CSB-PA521713(CD207 Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds
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