| Объем | 50 мкл |
| Синонимы | CD59 molecule, complement regulatory protein |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P13987 |
| Иммуноген | Synthetic peptide of human CD59 |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB, IHC,ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:100-1:300 |
| Примечание | This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen affinity purification |
| Области исследований | Cardiovascular,Immunology,Signal transduction,Stem cells |
| Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA778176(CD59 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ?200)
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The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA778176(CD59 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ?200)
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Gel: 10%SDS-PAGE, Lysate: 40 ?g, Lane 1-3: Huvec cells, hela cells, SKOV3 cells, Primary antibody: CSB-PA778176(CD59 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds
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Наименование: CD59 Antibody.