CDK1 (Ab-161) AntibodyСпецификацияОбъем | 100 мкл | Синонимы | CDC28, CDC2A, CDK1, Cyclin-dependent kinase 1, | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P06493 | Иммуноген | Peptide sequence around aa.159~163 (T-Y-T-H-E) derived from Human CDC2. | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB, IF,WB:1:500-1:1000, IF:1:100-1:200 | Примечание | Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II.<br/><br/>Ukomadu C, et al.(2003) J Biol Chem, 278(7): 4840-6<br/>Morris MC, et al.(2002)J Biol Chem, 277(26): 23847-53<br/>Brown NR, et al.(1999)J Biol Chem, 274(13): 8746-56<br/>Liu Y, et al.(2004) J Biol Chem, 279(6): 4507-14<br/> | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. | Области исследований | Epigenetics and Nuclear Signaling,Neuroscience,Cell biology,Signal transduction | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from COLO cells using CDC2(Ab-161) Antibody and the same antibody preincubated with blocking peptide.
| Immunofluorescence staining of methanol-fixed Hela cells using CDC2(Ab-161) Antibody.
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