CDKN1B (Ab-10) AntibodyСпецификация| Объем | 100 мкл | | Синонимы | CDKN1B, CDN1B, Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinase inhibitor p27, KIP1 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P46527 | | Иммуноген | Peptide sequence around aa.8~12 (N-G-S-P-S) derived from Human p27Kip1. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC,WB:1:500-1:1000, IHC:1:50-1:200 | | Примечание | Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Positive regulator of cyclin D-dependent kinases such as CDK4. Regulated by phosphorylation and degradation events.<br/><br/>Le XF, et al. (2003)J Biol Chem.<br/>Connor MK, et al. (2003)Mol Biol Cell, 14(1): 201-13.<br/>McAllister SS, et al. (2003) Mol Cell Biol, 23(1): 216-28.<br/>Chopra S, et al. (2002)J Biol Chem, 277(36): 32413-6.<br/>Boehm M, et al. (2002)EMBO J, 21(13): 3390-401. <br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. | | Области исследований | Epigenetics and Nuclear Signaling,Cancer,Cell biology | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from A2780 cells using p27Kip1(Ab-10
 | Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using p27Kip1(Ab-10
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Наименование: CDKN1B (Ab-10) Antibody.