CACNA1H AntibodyСпецификация| Объем | 100 мкл | | Синонимы | CAC1H, CACNA1HB, calcium channel, voltage-dependent, alpha 1H subunit | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | O95180 | | Иммуноген | Synthesized peptide derived from internal of human CACNA1H. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB,WB:1:500-1:3000 | | Примечание | Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1Hgives rise to T-type calcium currents. T-type calcium channels belong to the low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite negative potentials, and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes.<br/><br/>Cribbs L.L., Circ. Res. 83:103-109(1998).<br/>Cribbs L.L., Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases.<br/>Williams M.E., J. Neurochem. 72:791-799(1999).<br/>" | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Neuroscience,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from A549 cells, using CACNA1H antibody.
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Наименование: CACNA1H Antibody.