Объем | 50 мкл |
Синонимы | Centriolar coiled-coil protein of 110 kDa (Centrosomal protein of 110 kDa) (CP110) (Cep110), CCP110, CEP110 CP110 KIAA0419 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | O43303 |
Иммуноген | Recombinant Human Centriolar coiled-coil protein of 110 kDa protein (1-280AA) |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB, IHC, Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200 |
Примечание | Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation (PubMed:17719545 PubMed:17681131, PubMed:23486064). Also involved in promoting ciliogenesis. May play a role in the assembly of the mother centriole subdistal appendages (SDA) thereby effecting the fusion of recycling endosomes to basal bodies during cilia formation (By similarity). Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2 (PubMed:16760425). |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen Affinity Purified |
Абревеатура | Centriolar coiled-coil protein of 110 kDa |
Области исследований | Cancer, Cell biology, Tags & Cell Markers |
Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: CCP110 antibody at 4.6µg/ml
Lane 1: Hela whole cell lysate
Lane 2: 293T whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 114, 112 kDa
Observed band size: 114 kDa
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Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA528588ESR2HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human colon tissue using CSB-PA528588ESR2HU at dilution of 1:100
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