Объем | 100 мкг |
Code NO# | 1A3B6 |
Синонимы | CD14, CD14 molecule |
Тип антител | Monoclonal Antibody |
Видовая специфичность | Human |
Uniport ID | P08571 |
Иммуноген | Recombinant CD14 Protein |
Источник | mouse |
Видовая специфичность 1 | Human |
Перекрестная реактивность | specific for Recombinant CD14 Protein denatured and native forms |
Применение | ELISA,IHC,Recommended dilution:IHC:1:50-1:500 |
Примечание | As a component of the innate immune system, the cell surface glycoprotein CD14 is a myelomonocytic differentiation antigen preferentially expressed on monocytes, macrophages, and activated granulocytes. CD14 exists as two forms, either anchored into the membrane by a GPI-anchor tail (mCD14) or present as a soluble form (sCD14) in normal serum and body fluids. CD14 was first described as a pattern recognition receptor for lipopolysaccharide (LPS) and a variety of ligands derived from different microbial sources, along with the co-receptors Toll-like receptor TLR 4 and MD-2. The binding of CD14 and LPS depends on the presence and catalytic activity of lipopolysaccharide-binding protein (LBP). Besides its endotoxin signaling function, CD14 has been proposed to be involved in various biological processes, including transportation of other lipids, cell-cell interaction during different immune responses, as well as recognition of apoptotic cells. Multiple transcript variants resulting from alternative splicing encode the same isoform of CD14. |
Изотип | IgG2b |
Метод очистки | >95%,Protein G purified |
Коньюгат | Non-conjugated |
Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Области исследований | Immunology,Stem cells |
Станица на сайте производителя | ссылка |
Immunohistochemistry of paraffin-embedded human lung using CSB-MA0048791A0m in 30ug/ml dilute concentrations.
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Immunohistochemistry of paraffin-embedded human testis using CSB-MA0048791A0m in 30ug/ml dilute concentrations.
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Immunohistochemistry of paraffin-embedded human kidney using CSB-MA0048791A0m in 30ug/ml dilute concentrations.
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Immunohistochemistry of paraffin-embedded human lung using CSB-MA0048792A0m in 30ug/ml dilute concentrations.
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Immunohistochemistry of paraffin-embedded human testis using CSB-MA0048792A0m in 30ug/ml dilute concentrations.
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Immunohistochemistry of paraffin-embedded human kidney using CSB-MA0048792A0m in 30ug/ml dilute concentrations.
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