Объем | 100 мкл |
Синонимы | CDC25M3, Dual specificity phosphatase Cdc25A, EC 3.1.3.48, M-phase inducer phosphatase 1, MPIP1 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P30304 |
Иммуноген | Synthesized non-phosphopeptide derived from human CDC25A around the phosphorylation site of serine 178 (Q-N-S(p)-A-P). |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB,WB:1:500-1:3000 |
Примечание | Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDK1 and stimulates its kinase activity. Also dephosphorylates CDK2 in complex with cyclin E, in vitro.<br/><br/>Galaktionov K.I.,Cell 67:1181-1194(1991).<br/>The MGC Project Team,Genome Res. 14:2121-2127(2004).<br/>Wegener S., Eur. J. Cell Biol. 79:810-815(2000).<br/> <br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Epigenetics and Nuclear Signaling,Cancer,Cell biology |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from Jurkat cells, using CDC25A (Ab-178) antibody.
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Western blot analysis of extracts from HeLa cells (Lane 2) and 293 cells (Lane 3), using CDC25A (Ab-178) antiobdy. The lane on the left is treated with synthesized peptide.
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