CDH1 AntibodyСпецификация| Объем | 50 мкл | | Синонимы | cadherin 1, type 1, E-cadherin (epithelial) | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P12830 | | Иммуноген | Synthetic peptide of human CDH1 | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC,ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:100-1:300 | | Примечание | This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antigen affinity purification | | Области исследований | Cancer,Developmental biology,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA164023(CDH1 Antibody) at dilution 1/100, on the right is treated with synthetic peptide. (Original magnification: ?200)
 | The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA164023(CDH1 Antibody) at dilution 1/100, on the right is treated with synthetic peptide. (Original magnification: ?200)
 | Gel: 8%SDS-PAGE, Lysate: 40 ?g, Lane: Human brain malignant glioma tissue, Primary antibody: CSB-PA164023(CDH1 Antibody) at dilution 1/1750, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
 | | | |
Информация для заказа |
Наименование: CDH1 Antibody.